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Abstract: The optimal management of elderly patients with glio- blastoma multiforme (GBM) remains controversial, as no evidence-based standard of care exists for this unique subpopulation. These patients typically have a poor prognosis and high rates of treat-

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ACG Clinical Guideline: Management of Patients …

colon can present with melena (black, tarry stools) (5). In addition, hematochezia can be seen in patients with brisk upper gastrointestinal bleeding (UGIB).

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ACG Clinical Guideline: Management of Patients …

well as review of clinical trials and reviews known to the authors were performed for preparation of this document. The GRADE system was used to grade the strength of recommendations and the quality