The Birch reduction - Baran Lab

Lisa M. Barton The Birch Reduction Baran Group Meeting 3/10/18 Aromatic Esters OOR R RCO2R • Limitations include competitive carbonyl reduction •1-2 equiv. H2O or tBuOH added before Na in NH3 can prevent (doesn't work for methyl esters or those with 4-

  Reduction, Birch, The birch reduction