BIOPHARMACEUTICS CLASSIFICATION SYSTEM

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BIOPHARMACEUTICS CLASSIFICATION SYSTEMBasic Absorption and DispositionDrug at Absorption SiteDrug in BodyExcreted DrugMetabolitesabsorptionmetabolismexcre tionClinical Pharmacokinetics, Rowland and Tozer, 2nd Ed, Lea & Febiger, 1989These models use curve-fitting techniques to estimate kinetic rate constants and other parameters from time-course data for blood, tissue, or excreta; however, the curve-fitted parameters lack biological , J., Pharmac Ther, 12:537-562, 19812PharmacokineticsDISPOSITION OF DRUGSThe disposition of chemicals entering the body (from Klaassen, Casarett and Doull s toxicology , 5th ed.)

The disposition of chemicals entering the body (from C.D. Klaassen, Casarett and Doull’s Toxicology, 5th ed., New York: McGraw-Hill, 1996). ... Applications of BCS in oral drug delivery technology ... ♫Fortunately, extreme examples are the

  Applications, Example, Toxicology