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*CHAPTER 4Pathophysiologyand differential diagnosisof anaemiaJean-Fran ois Lambert, Photis (108-141):EBMT2008 4-12-2009 16:05 Pagina 1081. Definition and classification of anaemiasAnaemia is a common condition, particularly in young women and in the geriatricpopulation, and is a significant public health problem in developing is defined by the World Health Organisation as haemoglobin (Hb) < 120g/L in women and Hb < 130 g/L in men. This definition also includes the so-calledpseudo anaemic states (pregnancy, cardiac heart failure and hyperproteinaemia) whereHb concentration falls as the result of an increase of the plasma volume. Incontrast, a decreased red blood cell mass can be masked by haemoconcentrationresulting from a decrease in plasma deficiency is the most frequent cause of anaemia, closely followed by anaemiaof chronic disease (Figure 1).

1.Definitionandclassificationofanaemias Anaemiaisacommoncondition,particularlyinyoungwomenandinthegeriatric population, and is a significant public health problem in ...

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