GUIDELINES Post-Exposure Prophylaxis

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8*/5&3 5)& 4065)&3/ "'3*$"/ +063/"- 0' )*7 .&%*$*/& KEY SUMMARY POINTSn Southern Africa differs from other regions, particularly in terms of very high HIV and hepatitis B Post-Exposure Prophylaxis (PEP) GUIDELINES lack a substantive evidence base to guide advice. It is extremely unlikely that this will change, as randomised studies of different drug regimens for PEP are not feasible owing to the complexity of exposure , low event rate, and inability to ethically have a placebo group.

8*/5&3 5)& 4065)&3/ "'3*$"/ +063/"- 0' )*7 .&%*$*/& sustained a mucocutaneous blood risk exposure.3 Again

  Post, Exposure, Post exposure