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HIGHLIGHTSOF PRESCRIBINGINFORMATION Hyperglycemia …

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HIGHLIGHTS OF prescribing INFORMATIONThese highlights do not include all the information needed to use TOUJEO safely andeffectively. See full prescribing information for TOUJEO .TOUJEO (insulin glargine injection) U-300, for subcutaneous useInitial Approval: 2015 RECENT MAJOR CHANGES Dosage and Administration ( , )3/2018Warnings and Precautions ( , )3/2018 INDICATIONS AND USAGE TOUJEO is a long-acting human insulin analog indicated to improve glycemic control in adults withdiabetes mellitus. (1)Limitations of Use:Not recommended for treating diabetic ketoacidosis. (1) DOSAGE AND ADMINISTRATION Individualize dose based on type of diabetes, metabolic needs, blood glucose monitoringresults and glycemic control goal. ( , , ) Administer subcutaneously once daily at any time during the day, at the same time every day.

FULL PRESCRIBING INFORMATION: CONTENTS* 1 INDICATIONS AND USAGE 2 DOSAGE AND ADMINISTRATION 2.1 Important Administration Instructions 2.2 General Dosing Instructions 2.3 Starting Dose in Insulin-Naive Pediatric and Adult Patients 2.4 Starting Dose in Pediatric and Adult Patients with Either Type 1 or Type 2 Diabetes Already on Insulin Therapy

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