IFCC international conventional reference …

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Clin Chem Lab Med 2011;49(8):1275 1281 2011 by Walter de Gruyter Berlin Boston. DOI in press - uncorrected proofIFCC international conventional reference procedure for themeasurement of free thyroxine in serumInternational Federation of Clinical Chemistry and Laboratory Medicine( ifcc ) Working Group for Standardization of Thyroid Function Tests(WG-STFT)1)Sofie K. Van Houcke1, Katleen Van Uytfanghe1,Eri Shimizu2, Wataru Tani2, Masao Umemoto2andLinda M. Thienpont1,*1Laboratory for Analytical Chemistry, Faculty ofPharmaceutical Sciences, Ghent University, Ghent, Belgium2Laboratory of reference Material Institute for ClinicalChemistry Standards (ReCCS), Kawasaki, Kanagawa,JapanAbstractThe ifcc Working Group for Standardization of ThyroidFunction Tests proposes a candidate international conven-tional reference procedure (RMP) for measurement of theamount-of-substance concentration of free thyroxine inplasma/serum at physiological pH and temperature( ).

1276 Van Houcke et al.: Free thyroxine conventional reference procedure Article in press - uncorrected proof um, it is unknown whether the T4 measured in the dialysate truly reflects the FT4 concentration in serum (3, 4).

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