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IMMUNOLOGY - Elsevier.com

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873IMMUNOLOGYGLOSSARY88THE IMMUNE RESPONSE SYSTEM92Innate and adaptive immunity92Cells and molecules involved in theimmune response93Antigen-recognition lymphoid cells (B and T lymphocytes) 93Granulocytes 98Macrophages 98Dendritic cells 98Natural killer cells 99Cytokines 99Accessory molecules 103Other molecules 104Apoptosis 105IMMUNOGLOBULINS105Properties, functions and reactions105Structure of immunoglobulin molecule108Clinical considerations109Paraprotein 109Macroglobulins 110Cryoglobulins 110Cold agglutinins 110Monoclonal antibodies 110COMPLEMENT111The complement system111Complement pathways111Complement deficiencies112HYPERSENSITIVITY112Classi fication112IMMUNODEFICIENCY115Primary immunodeficiency115B-cell disorders 115T-cell disorders 116Combined B- and T-cell disorders 116Neutrophil disorders 117Secondary immunodeficiency118Hypogammaglobulinaemi a 118T-cell deficiency 118Hypergammaglobulinaemia 119AUTOIMMUNE DISEASE120Explanatory theories for breakdown inself tolerance121Autoantibodies1

(MALT) Natural killer Type of cytotoxic lymphocyte that has the intrinsic (NK) cell ability to recognize and destroy virally infected cells and some tumour cells. Specializes in killing cells that express little or no MHC molecule. NfkB A transcription factor which is widely used by different leucocyte populations to signal activation.

  Immunology, Malt

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