Infusion Reactions

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E10 April 2010 Volume 14, Number 2 Clinical Journal of Oncology NursingAt a GlanceMonoclonal antibodies have a unique potential for a non- allergic Infusion reaction caused by cytokine and expert management of a cytokine-release re- action may enable patients to be rechallenged with the mono-clonal antibody, potentially improving clinical safety of rapid infusions of rituximab is under investiga- tion, and initial findings of several trials reported that after successful first-cycle dosing according to manufacturer s protocol, subsequent doses may be delivered by rapid Infusion . Cancer therapies administered by IV Infusion may cause Infusion Reactions . Infusion Reactions always involve the immune system; however, some (of-ten called anaphylactic) are allergic in nature and typically are mediated by immunoglobulin E (IgE), whereas others (anaphylactoid) are not true allergic Reactions and are not mediated by IgE (Kemp, Lockey, & Simons, 2008).

Clinical Journal of Oncology Nursing • Volume 14, Number 2 • Infusion Reactions: Diagnosis, Assessment, and Management E11 measures, administration monitoring, severity grading, man-

  Reactions, Infusion, Infusion reactions