MATERIAL SAFETY DATA SHEET - pfizer.com

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1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKINGMaterial Name: Docetaxel InjectionTrade Name:Not applicableChemical Family:Not determinedIntended Use:Antineoplastic2. HAZARDS IDENTIFICATIONAppearance:Clear, colorless to pale yellow solutionSignal Word:DANGERStatement of Hazard:Flammable liquid and of causing genetic damage fertility or the unborn cause harm to breastfed Hazard Information:Short Term:May cause eye irritation (based on components) .Long Term:Repeat-dose studies in animals have shown a potential to cause adverse effects on centralnervous system, gastrointestinal system, blood and blood forming organs, and Clinical Effects:Common adverse effects include blood cell changes, nervous system/brain toxicity(neurotoxicity). Serious allergic reactions, including anaphylaxis, have been Indication of danger:Toxic to reproduction: Category 1Mutagenic: Category 3IrritantEU Hazard Symbols:EU Risk Phrases:R10 - - May cause harm to the unborn - Possible risk of irreversible - May cause harm to breastfed Hazard Classification(NOHSC):Hazardous Substance.

MATERIAL SAFETY DATA SHEET _____ Hazardous Combustion Products: Formation of toxic gases is possible during heating or fire. Fire Fighting Procedures: During all fire fighting activities, wear appropriate protective equipment, including self- contained breathing apparatus.

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