Phylogenetic Tree Computation Tutorial

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15/6/02Frank Olken - PGA PhylogenyTutorial1Phylogenetic TreeComputation TutorialFrank OlkenLawrence Berkeley National LabPresentation to PGA CourseMay 3, 2002Berkeley, California5/6/02Frank Olken - PGA PhylogenyTutorial2Overview Introduction: What? Why? ... Multiple Sequence Alignment Computing Phylogenetic Trees Merging Trees Resources Funding Sources25/6/02Frank Olken - PGA PhylogenyTutorial3Introduction5/6/02Fran k Olken - PGA PhylogenyTutorial4Example Seq. A = A A C C G G T T Seq. B = A A C C G G T G Seq. C = A C C C G G T C Seq. D = A C C C G G T AABCDABCDUnrootedTreeRootedTree35/6/02Fr ank Olken - PGA PhylogenyTutorial5Similarity vs. Homology Similar sequences resemble one another Homolog sequences derived from common ancestor Ortholog homologous sequences within a species Paralog homologous sequences between species5/6/02Frank Olken - PGA PhylogenyTutorial6Ortholog vs.

3 5/6/02 Frank Olken - PGA Phylogeny Tutorial 5 Similarity vs. Homology • Similar – sequences resemble one another • Homolog – sequences derived from common ancestor

  Tree, Tutorials, Computation, Similarity, Phylogenetic tree computation tutorial, Phylogenetic