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Re Dosing Guidelines for Complex casesCases longer than 4 hoursThe following are re Dosing Guidelines based on AntibioticsRe- Dosing IntervalCefazolin4 hoursCefoxitin4 hoursCiprofloxacin8 hoursClindamycin6hourspatients with normal renal function:Clindamycin6hoursErtapenem24 hoursGentamicin8 hours*Metronidazole8 hoursVancomycin12 hours***=Renal insufficiency (CrCl<50ml/min): 12 hoursFirst dose of antibiotic Should be within 1 hr prior toIncision time Renal insufficiency (CrCl50ml/min): 12 hours(CrCl <30ml/min, HD/CRRT): 24 hours**= Renal insufficiency (CrCl <30ml/min, HD/CRRT): 24 hoursABxABxDocument antibiotic, re dose and time At time of 1stDose document/mark on Anesthesia Record the time for re dosingUpdated 2/21/2011 Antibiotics SubcommitteePage 1 of 2Antibiotic Prophylaxis:The Antibiotic Surgical Care Improvement Project (SCIP) measures include the following:Type of SurgeryAntimicrobial Recommendationspy1. Antibiotic received within one hour prior to surgical incision,2.

Re‐Dosing Guidelines for Complex cases Cases Longer than 4 hours The following are redosing guidelines based on Antibiotics Re-dosing Interval Cefazolin 4 hours

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