T CELL LYMPHOMA ANALYSIS - Cytometry
1Charles Goolsby, PhDT CELL LYMPHOMA ANALYSISCharles Goolsby, E. Patterson Research Professor of PathologyNorthwestern Feinberg School of Goolsby, PhDT CELL LYMPHOMA ANALYSIS Diverse group of malignancies Pathology/clinical driven Extranodal Extranodal NK/T-cell LYMPHOMA , nasal type Enteropathy-type T-cell LYMPHOMA Hepatosplenic T-cell LYMPHOMA Subcutaneous panniculitis-like T-cell LYMPHOMA Cutaneous Blastic NK-cell LYMPHOMA Mycosis fungoides/Sezary syndrome Primary cutaneous anaplastic large cell LYMPHOMA Nodal Peripheral T-cell LYMPHOMA , unspecified Angioimmunoblastic T-cell LYMPHOMA Anaplastic large cell Aberrant immunophenotypes Significant overlap with patterns that can be seen in reactive Clonality V /V region family specific antibodies Sensitive.
5 Charles Goolsby, PhD T CELL LYMPHOMA ANALYSIS: Mycosis Fungoides/Szeary Syndrome • Immunophenotype – Mature T cell malignancy (surface CD3+) • Altered CD3 expression can be seen
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