以心臟科醫師的角度來看糖尿病 ... - tsim.org.tw
2013 24 12-18. . 1 1 1 1,2 1,2 1,2 1,2 1,2. 1. . 2. . . . UKPDS (Biguanides) (Sulfonylurea) (Insulin) . Thiazolidinedione (TZD) . Rosiglitazone . ( -glucosidase inhibitors) . DPP-4 (Dipeptidyl Peptidase-IV Inhibitors) 1 . (GLP-1) DPP-4 GLP-1 . (surrogate markers) ACCORD VADT HbA1c . . (A Patient-Centered Approach) . (individualization of treatment) . . HbA1C < 7% DPP-4 . GLP-1 . (Diabetes mellitus). (Anti-diabetic drugs). (Coronary artery disease). (Cardiovascular disease). . 6% 40 80 . . 40 . (HbA1c) 1,2 . . . 80708 100 . 012-018_1132 12 2013/3/11 04:41:24. 13. 2 . HbA1c . 3. 2 . 4. 2 4 . . . . 5,6. . DCCT/ . DEIT . 7-9. . Kumamoto UKPDS (Sulfonylurea). . 10-13. (legacy effect) . (metabolic memory) UKPDS 11,12,27,28 . DCCT/DEIT . 10 . 14,15. 12% . UKPDS . 11. . . 13. ACCORD, ADVANCE, . VADT Metformin Gliclazide . 16-19. 29 . 16 . HbA1c Glyburide . 1% HbA1c 18% Metformin 30 . ; 1% HbA1c 14% ADVANCE.
以心臟科醫師的角度討論糖尿病藥物使用 13 疾病等；以及小血管病變，包括視網膜病變、 腎病變和神經相關病變等。
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