Assessing drug synergy in combination therapies

Null-hypotheses are based on the observed drug response not a model of mechanism. If “Synergy” means “stronger than my mechanistic model predicts”, then: (1) a genuinely powerful combination isn’t classed as synergistic if it is predictable (2) synergy/antagonism changes as your knowledge and model changes.

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COVID-19 Guide | AMA

Exemptions based on religious or philosophic grounds, or personal belief, endanger the health of the unvaccinated individual and the health of those in his or her group and the community at large. The CDC offers resources for talking to parents about vaccines. On combating the spread of vaccine misinformation:

  Based

Clinical management of severe acute respiratory infection ...

Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected Interim guidance 13 March 2020 This is the second edition (version 1.2) of this document, which was originally adapted from Clinical management of severe