1 Basics of Cell Signaling - Wiley-VCH

1 Basics of Cell Signaling : Why, When and Where?One characteristic common to all organisms is the dynamic ability tocoordinate constantly their activities with environmental function of communicating with the environment is achievedthrough a number of pathways that receive and process signals ori-ginating from the external environment, from other cells within theorganism and also from different regions within the addition to adapting the function of an organism to environ-mental changes in a signal-directed way, other essential features ofmulticellular organisms require the coordinated control of cellularfunctions as formation and maintenance of the specialized tissues of mul-ticellular organisms depend on the coordinated regulation of cellnumber, cell morphology, cell location and expression of differen-tiated functions. Such coordination results from a complex networkof communication between cells in which signals produced affect tar-get cells where they are transduced into intracellular biochemical re-actions that dictate the physiological function of the target cell ( ).

1.1). The basis for the coordination of the physiological functions within a multicellular organism is intercellular signaling (or intercel-lular communication), which allows a single cell to influence the be-havior of other cells in a specific manner. As compared to single-cell organisms, where all cells behave similarly within a broad frame,

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