Transcription of #1: Examples of unethical trials - Centre for Research on ...
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#1: Examples of unethical trials - Centre for Research on ...
Examples of unethical trials Contents Ethical General observations ..3 ART treatment interruption trials ..3 Tenofovir trials on HIV Hepatitis E vaccine trial in Nevirapine PMTCT trials in Uganda ..6 SFBC Miami test Centre ..7 Letrozole trials in India ..7 Alosetron trials after marketing Streptokinase trials in India ..8 Fortified ORS trials in Risperidone trials in India ..9 VGV-1 trials in TGN 1412 trials in London ..10 Imatinib trials ..11 Ragaglitazar trials in India and other countries .12 Trovafloxacin trials in Nigeria ..12 Cilansetron trials in India ..13 Zoniporide trials in India ..14 Maxamine trial in Russia ..14 trials on foster care children in New Cilostazol trials in NDGA trials in Cariporide trial in Argentina ..16 SOMO briefing paper on ethics in clinical trials #1: Examples of unethical trials February 2008 (updated) Introduction This briefing paper provides an overview of known Examples of unethical clinical trials .
The Data and Safety Monitoring Board (DSMB) also found that treatment interruption was associated with a higher risk of disease progression. Enrolment in the SMART trial was halted two months earlier, in January 2006, and re-initiation of interrupted therapy was recommended.
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