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1 Introduction to cell biology - Stanford University

1 Introduction to cell MotivationWhy is the understanding of cell mechancis important?cells need to move andinteract with their environment cells have components that are highly dependent onmechanics, , structural proteins cells need to reproduce / divide to improvethe control/function of cells to improve cell growth/cell production medical appli-cations mechanical signals regulate cell metabolism treatment of certain diseasesneeds understanding of cell mechanics cells live in a mechanical environment itdetermines the mechanics of organisms that consist of cells directly applicable tosingle cell analysis research to understand how mechanical loading affects cells, cell differentation, cell morphology to understand how mechanically gated ionchannels work an understanding of the loading in cells could aid in developing struc-tures to grow cells or organization of cells more efficiently can help us to understandmacrostructured behavior better can help us to build machines/sensors similar tocells can help us understand the biology of the cell cell growth is affected by stressand mechanical properties of the substrate the cells are in understanding mechan-ics is important for knowing how cells move and for figuring out how to change cellmotion when building/engineering tissues, the tissue must have the necessary me-chanical properties understand how cells is

1 Introduction to cell biology 1.1 Motivation ... hoek was the first person to ever observe a cell under a microscope in 1674. The cell theory biologists use nowadays dates back to major contributions of Schwann and Schleiden in 1839, enhanced by contributios of Virchow in 1858.

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