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100 Years Since 1918: Are We Ready for the Next Pandemic?

100 Years Since 1918: Are We Ready for the next pandemic ? Daniel B. Jernigan, MD MPH. Director, Influenza Division centers for disease control and prevention Influenza Division Today's Agenda Remembering the 1918 pandemic Reviewing current influenza threats Evaluating pandemic readiness Gathering input on 1918 commemoration activities Influenza Division Significant Annual Burden of Influenza in Humans Influenza United States Global 12,000 56,000 Deaths 291,000 646,000. 140,000 710,000 Severe Cases 3M to 5M. Hospitalizations Cases B. ; ; Iuliano et al Lancet 2017. Shift: Reassortment of Influenza Viruses Influenza Division Human Avian or Influenza Swine Virus Influenza Reassorted Influenza Virus Virus with pandemic Potential Human-adapted viruses can arise from reassortment to cause efficient and sustained transmission Four pandemics in last 100 Years Influenza A Viruses Since 1918 Influenza Division All four pandemics in last 100 Years have had some 2009 pandemic genes that originated from avian influenza viruses (2009).

Centers for Disease Control and Prevention. Influenza Division Today’s Agenda Remembering the 1918 pandemic Reviewing current influenza threats Evaluating pandemic readiness Gathering input on 1918 commemoration activities. Significant …

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