Transcription of 12 Solid/solid mixing - Particle technology learning resources
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12 Solid/solid mixing - Particle technology learning resources
12 Solid/solid mixing The mixing of solids is a critically important operation in many industries, especially in pharmaceutical production where the active ingredient in a formulation may be toxic and be present at only by mass overall. A product with too low an active ingredient will be ineffective and a product with too high active ingredient may be lethal. To provide good solid mixing the phenomenon to be avoided, or overcome, is the particles tendency to segregate. Segregation occurs when a system contains particles with different sizes, densities, etc. and motion can cause particles to preferentially accumulate into one area over another; large particles work their way to the top of breakfast cereal fines are found at the bottom of the packet.
12 Solid/solid mixing The mixing of solids is a critically important operation in many industries, especially in pharmaceutical production where the active
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