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17 Hepatitis A

143 Hepatitis AHepatitis ADecember 2013 Green Book Chapter 17 v2_017 Hepatitis A NOTIFIABLEThe diseaseHepatitis A is an infection of the liver caused by Hepatitis A virus. The disease is generally mild, but severity tends to increase with age. Asymptomatic disease is common in children. Jaundice may occur in 70 80% of those infected as adults. Fulminant Hepatitis can occur but is rare. The overall case fatality ratio is low but is greater in older patients and those with pre-existing liver disease. There is no chronic carrier state and chronic liver damage does not virus is usually transmitted by the faecal oral route through person-to- person spread or contaminated food or drink.

146 Hepatitis A Hepatitis A December 2013 Green Book Chapter 17 v20 Combined hepatitis A and typhoid vaccine Combined vaccines containing purified inactivated ...

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