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18 Selenium - Portal Rasmi Kementerian Kesihatan Malaysia

18 selenium Introduction Selenium (Se) is derived from the Greek word selene meaning moon goddess. It was discovered by Jacob Berzelius of Sweden in 1817. In the 1950s, grazing animals suffering from disorders manifested as muscular dystrophy and liver necrosis were corrected with Selenium supplementation. Selenium in humans is mainly present as selenocysteine that is responsible for the functions of numerous mammalian proteins. The first selenoprotein to be identified was glutathione peroxidase (GSHPx) in 1973, which catalyzes the breakdown of toxic hydroperoxides. There are four antioxidant glutathione peroxidases that are capable of reducing a variety of organic hydroperoxides to their corresponding alcohol.

18 Selenium 18.1 Introduction Selenium (Se) is derived from the Greek word selenemeaning moon goddess.It was discovered by Jacob Berzelius of Sweden in 1817. In the 1950s, grazing animals

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