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2.2.8. VISCOSITY - uspbpep.com

EUROPEAN PHARMACOPOEIA Capillary viscometer methodThespecific optical rotationof a liquid is the angleof rotation , expressed in degrees ( ), of the plane ofpolarisation at the wavelength of the D-line of sodium( = )measuredat20 Cintheliquidsubstancetobe examined, calculated with reference to a layer of 1 dmand divided by the density expressed in grams per optical rotationof a substance in solutionis the angle of rotation , expressed in degrees ( ), of theplane of polarisation at the wavelength of the D-line ofsodium ( = nm) measured at 20 C in a solution ofthe substance to be examined and calculated with referenceto a layer of 1 dm containing 1 g/ml of the specific optical rotation of a substance in solutionis always expressed with reference to a given solvent the conventional system adopted by the Pharmacopoeiathe specific optical rotation is expressed by its valuewithout units; the actual units, degree millilitres perdecimetre gram [( ) ml dm 1 g 1] conversion factor from the International System to thePharmacopoeia system is the following:In certain cases specified in the monograph the angle ofrotation may be measured at temperatures other than 20 Cand at other polarimeter must be capable of giving readings to thenearest.

EUROPEAN PHARMACOPOEIA 5.0 2.2.9. Capillary viscometer method The specific optical rotation of a liquid is the angle of rotationα, expressed in degrees (°), of the plane of polarisation at the wavelength of the D-line of sodium

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