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2.2. PHYSICAL AND PHYSICOCHEMICAL METHODS

EUROPEAN PHARMACOPOEIA Clarity and degree of opalescence of PHYSICAL ANDPHYSICOCHEMICAL METHODS01/2008 CLARITY AND degree OFOPALESCENCE OF LIQUIDSVISUAL METHODU sing identical test-tubes of colourless, transparent, neutralglass with a flat base and an internal diameter of 15-25 mm,compare the liquid to be examined with a reference suspensionfreshly prepared as described below, the depth of the layerbeing 40 mm. Compare the solutions in diffused daylight 5 minafter preparation of the reference suspension, viewing that reference suspension I can readily be distinguishedfromwater R, and that reference suspension II can readily bedistinguished from reference suspension its clarity is the same as thatofwater Ror of the solvent used when examined under theconditions described above, or if its opalescence is not morepronounced than that of reference suspension sulfate Rinwater Rand dilute to mL with the samesolvent.

2.2.2. Degree of coloration of liquids EUROPEAN PHARMACOPOEIA 7.0 dilute suspensions containing small particles. Linearity between turbidity and concentration must be established by constructing

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  Methods, Liquid, Degree, Physical, Physicochemical, Physical and physicochemical methods, Degree of coloration of liquids, Coloration

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