Transcription of 2.6.12. MICROBIOLOGICAL EXAMINATION OF …
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2.6.12. MICROBIOLOGICAL EXAMINATION OF …
Depressor substancesEUROPEAN PHARMACOPOEIA and note whether the contractions producedby the preparation with the added histamine correspond tothe amount of histamine added. If this is not the case, or ifthe contractions caused by the substance to be examinedare not reproducible or if subsequent responses to high and low doses of histamine are diminished, the results ofthe tests are invalid and the test for depressor substances( ) ASodium gPotassium gCalcium chloride, gMagnesium chloride, gDisodium hydrogen phosphate gWater for injections Rsufficient to produce1000 mlSolution BSolution mlAtropine mgSodium hydrogen gGlucose gWater for injections Rsufficient to produce1000 mlSolution B should be freshly prepared and used within 24 DEPRESSOR SUBSTANCESC arryoutthetestonacatweighingnotlessthan2 kgandanaesthetised with chloralose or with a barbiturate thatallows the maintenance of uniform blood pressure.
EUROPEAN PHARMACOPOEIA 6.0 2.6.12. Total viable aerobic count TheMostProbableNumber(MPN)methodisreserved for bacterial counts when no other method is available.
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