2008 JMPR Evaluations-- PART I

Lambda-cyhalothrin 549 LAMBDA-CYHALOTHRIN (146) First draft prepared by Mr. Christian Sieke, Federal Institute for Risk Assessment, Berlin, Germany EXPLANATION Lambda-cyhalothrin is being evaluated as a new active substance intended as a replacement for cyhalothrin. Lambda-cyhalothrin is an enriched isomeric form of the two biologically active diastereoisomeric pairs of isomers of cyhalothrin. It is mainly used for plant protection purposes as a non-systemic broad spectrum insecticide in a wide range of crops worldwide. Data to support the uses reported and which are required for the estimation of MRLs have been provided by the company. The governments of Australia, Japan and Thailand have submitted national GAP and residue information. IDENTITY ISO common name lambda-cyhalothrin (draft E-ISO) lambda-cyhalothrine (draft F-ISO) IUPAC 1:1 mixture of (S)- -cyano-3-phenoxybenzyl-(Z)-(1R,3R)-3-(2- chloro-3,3,3-trifluoroprop-1-enyl) -2,2-dimethylcyclopropane carboxylate and(R)- -cyano-3-phenoxybenzyl (Z)-(1S,3S)-3-(2-chloro-3,3,3-trifluorop rop-1-enyl) -2,2-dimethylcyclopropane carboxylate CA [1- (S*),3 (Z)]-( )-cyano(3-phenoxyphenyl)methyl-3-(2-chlo ro-3,3,3-trifluoro-1-propenyl)-2,2-dimet hyl

550 Lambda-cyhalothrin PHYSICAL AND CHEMICAL PROPERTIES Table 1 Physical and chemical properties Property Results Method (test material) Reference Melting point

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