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4.1.3. BUFFER SOLUTIONS

EUROPEAN PHARMACOPOEIA BUFFER solutionsZirconium standard solution (1 g/L Zr). nitrate Requivalent to g ofZrO(NO3)2,2H2 Oinamixtureof2volumesofhydrochloricacid Rand 8 volumes ofwater Rand dilute to mL withthe same mixture of BUFFER SOLUTIONSB uffered acetone g ofsodium acetate Rand 42 g ofsodiumchloride Rinwater R, M hydrochloric acidand 150 mL ofacetone Rand dilute to 500 mL withwater solution pH g ofpotassium chloride Rinwater Rand mL M hydrochloric acid. Dilute to mL withwater BUFFER solution pH g ofdisodium hydrogen phosphate Rand gofpotassium dihydrogen phosphate Rinwater Rand diluteto mL with the same solvent.

4.1.3. Buffer solutions EUROPEAN PHARMACOPOEIA 7.0 Succinate buffer solution pH 4.6.4001500. Disssolve 11.8 g ofsuccinic acid R in a mixture of 600 mL of water R and 82 mL of 1 M sodium hydroxide and dilute to 1000.0 mL with water R. Acetate buffer solution pH 4.7. 4001600. Dissolve 136.1 g ofsodium acetate R in 500 mL of water R. Mix 250 mL of this …

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