Transcription of A Brief History of the Microscope and its ... - SPIE
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A Brief History of the Microscope and its ... - SPIE
Chapter 1. A Brief History of the Microscope and its Significance in the Advancement of Biology and Medicine This chapter provides a historical foundation of the field of microscopy and out- lines the significant discoveries in the fields of biology and medicine that are linked to the Microscope . Microscopes, which are devices to image those objects that are invisible to the naked eye, were transformed from interesting instruments used by hobbyists to serious scientific instruments used to explore and understand the mi- croscopic world. Because the technique of fluorescence microscopy is a major, if not the most widely used, application of both confocal microscopy and multiphoton ex- citation microscopy, I present a series of key developments of fluorescence micros- copy .
copy. Microscopy began with the observation of live specimens and continues its growth with technical developments in the fields of intravital microscopy, endos-copy, and in vivo microscopy. In this chapter, I cite and discuss many of the ad-vances in both biology and medicine that critically depended on the development
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