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A comparative study of the in-vitro dissolution profiles ...

Journal of Applied Pharmaceutical Science 02 (05); 2012: 52-59 ISSN: 2231-3354 Received on: 30-04-2012 Revised on 04-05-2012 Accepted on: 13-05-2012 DOI: Hassouna Chemistry Department, Faculty of Science, Beni Seuf University, Beni Seuf, Egypt. Issa Chemistry Department, Faculty of Science, Cairo University, Giza, Egypt. Zayed Head of Quality Control Department, October Pharma Co., 6th October City, Egypt. For Correspondence Hassouna Prof. of Analytical chemistry Chemistry Department, Faculty of Science, Beni Seuf University, Beni Seuf, Egypt . Tel.: +00201223861504 a comparative study of the in-vitro dissolution profiles of paracetamol and caffeine combination in different formulations using HPLC Hassouna, Issa and Zayed ABSTRACT dissolution testing is an in vitro technique of great importance in formulation and development of pharmaceutical dosage forms, as it can be used as a substitute for in vivo studies under strictly defined and s

Journal of Applied Pharmaceutical Science 02 (05); 2012: 52-59 Caffeine is almost completely metabolized in the liver by oxidation, demethylation and acetylation to various xanthine

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