Transcription of A direct approach to false discovery rates - genomine.org
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A direct approach to false discovery rates - genomine.org
J. R. Statist. Soc. B (2002). 64, Part 3, pp. 479 498. A direct approach to false discovery rates John D. Storey Stanford University, USA. [Received June 2001. Revised December 2001]. Summary. Multiple-hypothesis testing involves guarding against much more complicated errors than single-hypothesis testing. Whereas we typically control the type I error rate for a single-hypothesis test, a compound error rate is controlled for multiple-hypothesis tests. For example, controlling the false discovery rate FDR traditionally involves intricate sequential p-value rejection methods based on the observed data. Whereas a sequential p-value method fixes the error rate and estimates its corresponding rejection region, we propose the opposite approach we fix the rejection region and then estimate its corresponding error rate.
False Discovery Rates 481 quantitiestouse.Section9showshowtopickatuningparameterintheestimatesautomatically. Section 10 is the discussion, and Appendix A provides ...
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