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A Good Practice Guide to the Administration of Substances ...

JOURNAL OF APPLIED TOXICOLOGYJ. Appl. , 15 23 (2001)A good Practice Guide to the Administrationof Substances and Removal of Blood,Including Routes and VolumesKarl-Heinz Diehl1, Robin Hull2, David Morton3, Rudolf Pfister4, Yvon Rabemampianina5,David Smith6,*, Jean-Marc Vidal7and Cor van de Vorstenbosch81 Aventis, PO Box 1140, D35001 Marburg, Germany2N I B S C, Blanch Lane, South Miimms, Potters Bar, Hertfordshire EN6 3QG3 The University of Birmingham, Medical School, Edgbaston, Birmingham B15 2TT4 Novartis Pharma AG, CH-4002 Basel, Switzerland5 Centre de Recherche Pfizer, Etablissement d Amboise, Z1 Poce -sur-Cisse-BP 159 37401 Amboise Cedex, France6 AstraZeneca R&D Charnwood, Bakewell Road, Loughborough, Leics LE11 5RH7 Aventis, 102 Route de Noisy, 95235 Romainville Ce dex, France8N V Organon, PO Box 20, 5340 BH Oss, NetherlandsKey words: blood volumes; blood removal; Administration Substances .

JOURNAL OF APPLIED TOXICOLOGY J. Appl. Toxicol. 21, 15–23 (2001) A Good Practice Guide to the Administration of Substances and Removal of Blood,

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