Transcription of ACG and CAG Clinical Guideline: Management of Dyspepsia
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ACG and CAG Clinical Guideline: Management of Dyspepsia
988 The American Journal of GASTROENTEROLOGY VOLUME 112 | JULY 2017 GUIDELINES INTRODUCTION Descriptions of upper gastrointestinal symptoms date back thou-sands of years ( 1 ). Stomach disorders became an obsession of developed countries in the eighteenth century ( 2 ) when the term Dyspepsia was fi rst coined ( 3 ). A systematic review ( 4 ) reported that ~20% of the population has symptoms of Dyspepsia glob-ally. Dyspepsia is more common in women, smokers, and those taking non-steroidal anti-infl ammatory drugs ( 4 ). Patients with Dyspepsia have a normal life expectancy ( 5 ), however, symptoms negatively impact on quality of life ( 6,7 ) and there is a signifi cant economic impact to the health service and society ( 8 ).
H. pylori eradication should be offered in these patients if they are infected. We recommend PPI, TCA and prokinetic therapy (in that order) in those that fail therapy or are H. pylori negative. We do not recommend routine upper gastrointestinal (GI) motility testing but it may be useful in selected patients.
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