Transcription of Actinomycetes: Source, Identification, and Their Applications
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Actinomycetes: Source, Identification, and Their Applications
(2014) 3(2): 801-832 801 Review Article Actinomycetes: Source, identification , and Their Applications Mukesh Sharma*, Pinki Dangi and Meenakshi Choudhary Department of Biotechnology, Jaipur Institute of Biotechnology, Maharaj Vinayak Global University, Jaipur (Rajasthan) India *Corresponding author A B S T R A C T Introduction During 1914 to 1939, Selman A. Waksman had been consistently systematically screening soil bacteria and fungi to find an antibiotic for tuberculosis. In 1939, he discovers the effect of certain fungi specially actinomycetes on bacterial growth. In 1940, he was able to isolate an effective antibiotic, actinomycin and for this he got success in 1944, with the discovery of all this work in 1952, he got the Noble prize in physiological & medicine.
The bioactive secondary metabolites produced by microorganisms is reported to be around 23,000 of which 10,000 are produced by actinomycetes,thus representing 45% of all bioactive microbial metabolites discovered (Berdy 2005). Among actinomycetes, approximately 7,600 compounds are produced by Streptomyces species (Berdy 2005).
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