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Alcohol and Medication Interactions

Alcohol and MedicationInteractionsRon Weathermon, , and David W. Crabb, medications can interact with Alcohol , thereby altering the metabolism or effects ofalcohol and/or the Medication . Some of these Interactions can occur even at moderatedrinking levels and result in adverse health effects for the drinker. Two types of Alcohol - Medication Interactions exist: (1) pharmacokinetic Interactions , in which Alcohol interfereswith the metabolism of the Medication , and (2) pharmacodynamic Interactions , in whichalcohol enhances the effects of the Medication , particularly in the central nervous system( , sedation). Pharmacokinetic Interactions generally occur in the liver, where both alcoholand many medications are metabolized, frequently by the same enzymes.

mouth, a small amount is immediately broken down (i.e., metabolized) in the stomach. Most of the remaining alcohol is then absorbed into the bloodstream from the gastrointestinal tract, primar-ily the stomach and the upper small intestine. Alcohol absorption occurs slowly from the stomach but rapidly from the upper small intestine. Once

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