Alcohol and Medication Interactions

Alcohol and MedicationInteractionsRon Weathermon, , and David W. Crabb, medications can interact with Alcohol , thereby altering the metabolism or effects ofalcohol and/or the Medication . Some of these Interactions can occur even at moderatedrinking levels and result in adverse health effects for the drinker. Two types of Alcohol - Medication Interactions exist: (1) pharmacokinetic Interactions , in which Alcohol interfereswith the metabolism of the Medication , and (2) pharmacodynamic Interactions , in whichalcohol enhances the effects of the Medication , particularly in the central nervous system( , sedation).

ications that can inhibit ADH activity— such as aspirin and certain medications used to treat ulcers and heartburn (i.e., H 2 receptor antagonists, such as cime-tidine [Tagamet®], nizatidine [Axid®] and ranitidine [Zantac®])—experience reduced first-pass metabolism (Caballaria et al. 1991; Roine et al. 1990). Similarly,

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  Alcohols, Inhibits

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