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Alcohol and Medication Interactions

Alcohol and MedicationInteractionsRon Weathermon, , and David W. Crabb, medications can interact with Alcohol , thereby altering the metabolism or effects ofalcohol and/or the Medication . Some of these Interactions can occur even at moderatedrinking levels and result in adverse health effects for the drinker. Two types of Alcohol - Medication Interactions exist: (1) pharmacokinetic Interactions , in which Alcohol interfereswith the metabolism of the Medication , and (2) pharmacodynamic Interactions , in whichalcohol enhances the effects of the Medication , particularly in the central nervous system( , sedation). Pharmacokinetic Interactions generally occur in the liver, where both alcoholand many medications are metabolized, frequently by the same enzymes.

sedative effects of both alcohol and sedative medications can enhance each other (i.e., the effects are addi-tive), thereby seriously impairing a person’s ability to drive or operate other types of machinery. Most studies assessing alcohol-medication interactions focus on the effects of chronic heavy drinking. Relatively limited information ...

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