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Alcohol’s Harmful Effects on Bone

190 Alcohol Health & Research WorldAlcohol s Harmful Effects on BoneH. Wayne Sampson, alcohol consumption can interfere with bone growth and replacement of bone tissue( , remodeling), resulting in decreased bone density and increased risk of fracture. These effectsmay be exerted directly or indirectly through the many cell types, hormones, and growth factorsthat regulate bone metabolism. Alcohol consumption during adolescence reduces peak bone massand can result in relatively weak adult bones that are more susceptible to fracture. In adults, alco-hol consumption can disrupt the ongoing balance between the erosion and the remodeling ofbone tissue, contributing to alcoholic bone disease.

Vol. 22, No. 3, 1998 191 Figure 1 A section of the upper end of the long bone of the thigh (i.e., the femur). The ball at the upper left forms part of the hip joint. The walls of the shaft (C) are mainly cortical bone; the bone nearer the ends (T) is cancellous bone. C T 1Moderate drinking is generally defined as no more than two standard ...

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