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Alcohol’s Harmful Effects on Bone

190 Alcohol Health & Research WorldAlcohol s Harmful Effects on BoneH. Wayne Sampson, alcohol consumption can interfere with bone growth and replacement of bone tissue( , remodeling), resulting in decreased bone density and increased risk of fracture. These effectsmay be exerted directly or indirectly through the many cell types, hormones, and growth factorsthat regulate bone metabolism. Alcohol consumption during adolescence reduces peak bone massand can result in relatively weak adult bones that are more susceptible to fracture. In adults, alco-hol consumption can disrupt the ongoing balance between the erosion and the remodeling ofbone tissue, contributing to alcoholic bone disease.

p. 192) (Kanis 1994). As aging bones weaken, they reach a point (i.e., frac-ture threshold) at which even minor stress can cause fractures. Adolescent Bone Development and Alcohol Achieving an optimal peak bone mass during adolescence may reduce a per-son’s risk for developing osteoporosis (i.e., bone loss with fracture) later in life.

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