Transcription of Alcohol’s Impact on Kidney Function
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Alcohol’s Impact on Kidney Function
Cell s Function depends not only on receiving a continuous supply of nutrients and elimi-nating metabolic waste products butalso on the existence of stable physi-cal and chemical conditions in theextracellular fluid1bathing it. Amongthe most important substances con-tributing to these conditions are water,sodium, potassium, calcium, andphosphate. Loss or retention of anyone of these substances can influencethe body s handling of the others. Inaddition, hydrogen ion concentration( , acid-base balance) influencescell structure and permeability as wellas the rate of metabolic reactions. Theamounts of these substances must beheld within very narrow limits, re-gardless of the large variations possi-ble in their intake or loss.
mise kidney function, can interfere with kidney function directly, through acute or chronic consumption, or indirectly, as a consequence of liver disease. This article first reviews direct effects of alcohol on kidney structure, function, and regulation, highlighting relevant effects associated with liver disease. Following this
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