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Alternatives for Metoprolol Succinate

More.. Copyright 2009 by Therapeutic Research Center Reprinted with permission CR09334 Pharmacist s Letter / Prescriber s Letter ~ Box 8190, Stockton, CA 95208 ~ Phone: 209-472-2240 ~ Fax: 209-472-2249 ~ Detail-Document #250302 This Detail-Document accompanies the related article published in PHARMACIST S LETTER / PRESCRIBER S LETTER March 2009 ~ Volume 25 ~ Number 250302 Alternatives for Metoprolol Succinate Background Metoprolol tartrate (Lopressor) is a regular, immediate-release tablet, while Metoprolol Succinate (Toprol XL) is an extended-release ,2 A shortage of generic Metoprolol Succinate has necessitated switching some patients to alternative therapy.

bisoprolol group, worsening heart failure occurred in about 2% of patients. Serious adverse effects also occurred in about 2% of the metoprolol to bisoprolol patients. Adverse effects were higher in patients switched to the equivalent dose rather than half the equivalent dose. 12 Conclusion Whenever a medication becomes unavailable,

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