American Thoracic Societv

American Thoracic SocietvGuidelines for Methacholine and Exercise ChallengeTesting-1999 THIS OFFICIAL OF THE American Thoracic society WAS ADORED BY THE ATS BOARD OF DIRECTORS, JULY 1999I. Purpose and ScopeII. Methacholine Challenge TestingA. IndicationsB. ContraindicationsC. Technician Training/QualificationsD. SafetyE. Patient PreparationF. Choice and Preparation of MethacholineG. Dosing Protocols1. Two-Minute Tidal Breathing Dosing Protocol2. Five-Breath Dosimeter ProtocolH. Nebulizers and DosimetersI. Spirometry and Other End-point MeasuresJ. Data PresentationK. InterpretationIII. Exercise ChallengeA. IndicationsB. Contraindications and Patient PreparationC. Exercise Challenge TestingD. Assessing the ResponseReferencesAppendix A: Sample Methacholine Challenge Test ConsentFormAppendix B: Sample Methacholine Challenge Pretest Ques-tionnaireAppendix C: Sample Report FormatAppendix D: Equipment SourcesI.

for bronchial challenge testing (l-5) and reviews on the gen-eral topic of BHR (6-9). As with other American Thoracic Society (ATS) statements on pulmonary function testing, these guidelines come out of a consensus conference. The basis of discussion at the committee’s September 1997 meeting was a draft prepared by three members (P.E., C.I ...

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