Transcription of Amino Acid-Protecting Groups
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Amino Acid-Protecting Groups
1 Amino Acid-Protecting Groups Albert Isidro-Llobet,1 Mercedes lvarez,1,2,3* Fernando Albericio1,2,4* 1 Institute for Research in Biomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028-Barcelona, Spain. 2 CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028-Barcelona, Spain. 3 Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, 08028-Barcelona, Spain. 4 Department of Organic Chemistry, University of Barcelona, Mart i Franqu s 1, 08028-Barcelona, Spain. E-mail: RECEIVED DATE *Authors to whom correspondence should be addressed. Fax: 34 93 403 71 26. E-mail: Create PDF files without this message by purchasing novaPDF printer ( ) 2 Contents 1.
protection. 2.2. Introduction of the protecting groups As there are several types of α-amino-protecting groups, there is a wide range of protection methodologies. Most of these are based on the reaction of the free amino acids (side chain-protected if necessary, see ω-amino protection part for selective Lys and Orn side chain
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