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ANAL CANCER - Jones & Bartlett Learning

10/16/06 11:34 AM Page 1. ANAL CANCER . 5- fluorouracil Mitomycin radiation Therapy (Wayne State regimen)..2. 5- fluorouracil : 1000 mg/m2/day IV continuous infusion on days 1 4 and 29 32. Mitomycin: 15 mg/m2 IV on day 1. A. radiation therapy: 200 cGy/day on days 1 5, 8 12, and 5 19 (total dose, 3000 cGy). Chemotherapy is given concurrently with radiation therapy1,2. 5- fluorouracil Mitomycin radiation Therapy (European Organization for Research and Treatment of CANCER [EORTC] regimen) ..3. 5- fluorouracil : 750 mg/m2/day IV continuous infusion on days 1 5 and 29 33. Mitomycin: 15 mg/m2 IV on day 1. radiation therapy: 180 cGy/day over 5-week period (total dose, 4500 cGy). Chemotherapy is given concurrently with radiation therapy. If partial or complete response occurs, a boost of 1500 2000 cGy is given1 3.

1 A 5-Fluorouracil Mitomycin Radiation Therapy (Wayne State regimen).....2 5-Fluorouracil: 1000 mg/m2/day IV continuous infusion on days 1–4 and 29–32 ...

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