Transcription of Anatomy and Physiology of Peritoneal Dialysis
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Anatomy and Physiology of Peritoneal Dialysis
1 Anatomy and Physiology of Peritoneal Dialysis Isaac Teitelbaum, MDProfessor of MedicineDirector, Acute & Home Dialysis ProgramsUniversity of Colorado HospitalDenver, ColoradoOutline Peritoneal cavity as a Dialysis system Models of Peritoneal transport Physiology of Peritoneal transport Inverse relationship between solute transport and ultrafiltration Kinetics of Peritoneal transport Synthesis & Application Middle Molecules 3 Anatomy of The Peritoneum The lining of the abdominal cavity Two layers:parietal - lines the anterior wall and undersurface ofthe diaphragm - 20% of total SA; blood supply from abdominal wall visceral - covers the abdominal organs- 80% of total SA; blood supply from mesenteric aa and portal vv Gokal R, Textbook of PD, pp. 61-70 41. The two main properties of the Peritoneal membrane are:a. Semi permeable this allows substances of certain sizes to move from an area ofgreater concentration to less Bi Directional - substances move in either direction across the So-called lymphatic drainage refers to bulk flow from the Peritoneal cavity back to the circulation.
Outline • Peritoneal cavity as a dialysis system • Models of peritoneal transport • Physiology of peritoneal transport Inverse relationship between solute transport and ultrafiltration • Kinetics of peritoneal transport
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