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ANSWERING CAUSAL QUESTIONS USING OBSERVATIONAL …

1 1 OCTOBE R 2021. Scientific Background on the Sveriges Riksbank Prize in Economic Sciences in Memory of Alfred Nobel 2021. ANSWERING CAUSAL QUESTIONS USING OBSERVATIONAL DATA. The Committee for the Prize in Economic Sciences in Memory of Alfred Nobel THE ROYAL SWEDISH ACADEMY OF SCIENCES, founded in 1739, is an independent organisation whose overall objective is to promote the sciences and strengthen their influence in society. The Academy takes special responsibility for the natural sciences and mathematics, but endeavours to promote the exchange of ideas between various disciplines. BOX 50005 (LILLA FRESCATIV GEN 4 A), SE-104 05 STOCKHOLM, SWEDEN. TEL +46 8 673 95 00, ANSWERING CAUSAL QUESTIONS USING OBSERVATIONAL DATA. Most applied science is concerned with uncovering CAUSAL relationships. In many fields, randomized controlled trials (RCTs) are considered the gold standard for achieving this.

In medical science, the norm was, and still is, to estimate and report the intention-to-treat estimate: i.e., to analyze outcomes with individuals assigned to their initial treatment status, even if they deviated from that during the course of the trial.

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