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ANTICHOLINERGICS: Reference List - RxFiles

ANTICHOLINERGICS: Reference List of Drugs with Potential Anticholinergic Effects 1, 2, 3, 4, 5 J Bareham BSP Aug 2021 WHENEVER POSSIBLE, AVOID DRUGS WITH MODERATE TO HIGH ANTICHOLINERGIC ACTIVITY IN OLDER ADULTS (>65 YEARS OF AGE) Low Anticholinergic Activity; Moderate/High Anticholinergic Activity -B in combo Beers Antibiotics ampicillin *ALL AVAILABLE AS cefOXitin GENERIC clindamycin gentamicin (Oint & Sol n NIHB covered) piperacillin vancomycin Antidepressants amitriptyline ELAVIL clomiPRAMINE ANAFRANIL desipramine NORPRAMIN doxepin >6mg SINEQUAN imipramine TOFRANIL nortriptyline AVENTYL -less anticholinergic effects than amitriptyline & imipramine trimipramine SURMONTIL ---------------------------------------- ---------------------------------------- --------------- citalopram CELEXA

baclofen LIORESAL ( on intrathecal only) cyclobenzaprine FLEXERIL methocarbamol ROBAXIN OTC orphenadrine NORFLEX OTC tiZANidine Baclofen is the preferred agent of the above listed muscle relaxants however, it does display moderate to high anticholinergic activity. Opioids

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