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Appendix F: Guidelines for Standard Method Performance ...

2016 AOAC INTERNATIONALC ontentsIntroduction to Standard Method Performance Requirements 1 Annex A: Format of a Standard Method Performance Requirement 5 Annex B: Classification of methods 11 Annex C: Understanding the POD Model 12 Annex D: Definitions and Calculations of HorRat Values from Intralaboratory Data 13 Annex E: AOAC Method Accuracy Review 15 Annex F: Development and Use of In-House Reference Materials 16 Introduction to Standard Method Performance RequirementsStandard Method Performance Requirements (SMPRs ) are a unique and novel concept for the analytical methods community. SMPRs are voluntary consensus standards , developed by stakeholders, that prescribe the minimum analytical Performance requirements for classes of analytical methods . In the past, analytical methods were evaluated and the results compared to a gold Standard Method , or if a gold Standard Method did not exist, then reviewers would decide retrospectively if the analytical Performance was acceptable.

Working groups.—Working groups are formed by the stakeholder panel when a specific analytical topic has been identified. The primary purpose of a working group is to draft an SMPR. Working groups may also be formed to make general recommendations, such as developing a common definition to be used by multiple working groups.

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