Transcription of APPLICATION INFORMATION - sciex.com
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A-1929A. APPLICATION INFORMATION . Genetic Analysis: CEQ Series STRATEGIES FOR AUTOMATING THE REVIEW OF DATA. Mark Dobbs Beckman Coulter, Inc. One of the most time-consuming tasks in projects Definition of a Study . that call upon large numbers of independent data Within the context of the CEQ, a Study is defined sets is the segregation of data that is irrelevant or of as a collection of analyzed, non-sequencing results. poor quality from data that is useful. The task of This level of analysis, referred to as primary analy- selecting data that is relevant to a specific task in a sis to distinguish it from higher order levels of study, but may be of marginal or no value in other interpretation, consists of color separation, baseline tasks, is more difficult. For example, short normalization, dye mobility-shift correction and, in electrophoretic separations with size fragments that nearly all cases, fragment size determination and are less than or equal to 250 nucleotides in length allele assignment.
One of the most time-consuming tasks in projects that call upon large numbers of independent data sets is the segregation of data that is irrelevant or of
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