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ATTENUATED CYCLOPHOSPHAMIDE, THALIDOMIDE & …

Myeloma group ATTENUATED CYCLOPHOSPHAMIDE, THALIDOMIDE & DEXAMETHASONE (CTDa). INDICATIONS. First or subsequent-line chemotherapy for multiple myeloma Note: For standard risk older MM patients not suitable for transplantation either as initial therapy or at relapse. GENERAL PRE-ASSESSMENT. 1. Ensure all the following staging investigations are done: o FBC & film o Clotting screen o U&Es o LFTs o Calcium o Albumin o Uric acid o CRP. o Virology : HIV, Hepatitis B (including core antibody), and Hepatitis C. o Calculated creatinine clearance (CrCl), urine protein/ creatinine ratio o Electrophoresis and immunofixation for quantitation of serum paraprotein and immunoglobulins.

Myeloma group This is a controlled document and therefore must not be changed MM.9 CTD - attenuated Authorised by Myeloma lead Dr. Karthik Ramasamy July 2017

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