Transcription of Basic Pharmacokinetics Sample Chapter
{{id}} {{{paragraph}}}
Example: confidence
Basic Pharmacokinetics Sample Chapter
666 Extravascular routes of Drug remaining to be absorbed, or drugremaining at the site of Determination of elimination half life(t1/2) and elimination rate constant (KorKel) Absorption rate constant (Ka) Wagner Nelson method(one-compartment model) andLoo Riegelman method(two-compartment model) Lag time (t0) Some important comments on theabsorption rate The apparent volume of distribution (V) Time of maximum drug concentration,peak time (tmax) Maximum (peak) plasma concentration(Cp) Some general Example for extravascular route of Flip-flop kinetics126 ObjectivesUpon completion of this Chapter , you will have the ability to: calculate plasma drug concentration at any given time after the administration of an extravasculardose of a drug, based on known or estimated pharmacokinetic parameters interpret the plasma drug concentration versus tim
Extravascularroutesofdrugadministration 109 t = 0 Time (h) X a (mg) Intercept = (X a) 0 or FX 0 Slope = ÐK a 2.303 Time (h) t = 0 X a (mg) (a) (b) Figure6.4 ...
Loading..
Tags:
Information
Domain:
Source:
Link to this page:
Please notify us if you found a problem with this document: